BOTOX® Cosmetic, introduced in 2002, is the first botulinum toxin to be approved by the FDA to temporarily treat moderate to severe glabellar lines between the brows.
With real, noticeable results, no surgery and no recovery time, there are many reasons why BOTOX® Cosmetic has been chosen by millions of women and their doctors.
Approximately 11.8 million1 BOTOX® Cosmetic procedures have been administered in the United States since 2002.
92% of 303 patients surveyed were satisfied with the results of their BOTOX® Cosmetic experience2,3.
Why Does Skin Age?
Aging skin and wrinkles result from a combination of many factors. It’s not just about cellular changes, collagen depletion, hormone loss, or damage caused by free radicals. The 11s – those vertical lines that appear between your brows – result from muscle contractions. When you concentrate, squint, or frown, the muscles between your brows contract, causing your skin to furrow and fold. After years of frequent contraction, those wrinkles can linger even after the muscles are at rest.

Figure 1:
Relaxed glabellum muscles

Figure 2:
Contracted glabellum muscles
BOTOX® Cosmetic works by blocking nerve impulses to the injected muscles. This reduces muscle activity that causes the persistent lines to form between the brows.
How does BOTOX® Cosmetic work?
BOTOX® Cosmetic is a prescription medicine that is injected into muscles and used to improve the look of the “11s,” the moderate-to-severe frown lines between the eyebrows (glabellar lines). It works by blocking nerve impulses to the injected muscles. This reduces muscle activity that causes moderate to severe lines to form between the brows.
When will I see results from a BOTOX® Cosmetic treatment?
Within days, you may see a marked improvement in the moderate-to-severe frown lines between your brows. Lines continue to improve for up to 30 days, and results can last for up to 4 months. Individual results may vary.
How long does BOTOX® Cosmetic last?
Visible results have been shown to last up to 4 months. Your own results may vary – be sure to talk to Dr. Bradford about what you can expect and when to schedule your next appointment.
Is treatment with BOTOX® Cosmetic painful?
Discomfort is usually minimal and brief. Prior to injection, your physician may choose to numb the area with a cold pack or anesthetic cream. The entire procedure takes approximately 10 minutes. Most patients are in and out of the physician’s office without downtime following BOTOX® Cosmetic treatment.
Side effects associated with the injection include localized pain, infection, inflammation, tenderness, swelling, swelling, redness, and/or bleeding/bruising.
Will I still be able to make facial expressions?
Although the results are visible, a treatment with BOTOX® Cosmetic (onabotulinumtoxinA) will not radically change your facial appearance or make you look as if you’ve “had work done.” The muscle activity that causes frown lines between the brows is temporarily reduced, so you can still frown or look surprised without the wrinkles and creases between your brows.
What will happen to the moderate to severe frown lines between my brows if I choose not to continue treatments?
If you do not continue treatments, the moderate-to-severe frown lines between your brows will gradually return to the way they looked before treatment.
Is BOTOX® Cosmetic expensive?
According to the American Society of Plastic Surgeons, the average cost of BOTOX® Cosmetic is approximately $400. Please ask your physician or health care provider for more information as pricing may vary.
BEFORE AND AFTER